Cyclosporine and dental care
Cyclosporine is a recognized cause of drug-induced gingival overgrowth, and gingival hyperplasia is listed as an adverse reaction in the current cyclosporine prescribing information. Overgrowth tends to be more severe in transplant patients who are also taking a calcium channel blocker such as amlodipine or nifedipine, because both drug classes are independently associated with the effect. Cyclosporine also suppresses immunity, which affects healing and oral-infection risk, and it has multiple drug interactions that matter for dental prescribing — particularly clarithromycin and azole antifungals, which can raise cyclosporine exposure and should be coordinated with the clinician managing the medication.
Never start, stop, or change a medication based on what you read here. Bring questions to your dentist, physician, pharmacist, or prescribing clinician.
Medication snapshot
- Generic name
- Cyclosporine
- Brand names
- Sandimmune, Neoral, Gengraf
- Drug class
- Calcineurin inhibitor immunosuppressant
- Category
- Steroids and inflammation
- Common use
- Cyclosporine is an immunosuppressant used after organ transplant and for autoimmune conditions like severe psoriasis and rheumatoid arthritis.
- Dental topics covered
- 1 dental topic
Dental topics
Dental topics for Cyclosporine
Before your visit
What to tell your dentist
A photo of your medication bottle or your pharmacy printout helps. Here is the key information to share:
- You take Cyclosporine (Cyclosporine)
- You take this medication (name, dose, and how often)
- Why you take it
- Recent dose changes
- Any side effects you have noticed, such as dry mouth, nausea, or taste changes
- Upcoming dental surgery, implants, or extractions
- Other medications you take, including over-the-counter and supplements
KYT Framework
How KYT uses Cyclosporine in dental planning
Medications shape the clinical picture but do not automatically change what is possible. They inform the timing, method, and coordination of care.
Structure
Does Cyclosporine affect bone, gum tissue, saliva, enamel risk, or healing support?
Force
Will chewing, grinding, or bite pressure create added risk for vulnerable teeth or healing tissue?
Timing
Is this something to prevent now, monitor, or evaluate soon? Should coordination happen before treatment?
Stability
What plan gives the mouth the best chance to stay stable while managing this medication?
Taking Cyclosporine and planning dental care?
Bring your medication list to your visit so KYT can plan with the full picture.
臨床審閱：Dr. Isaac Sun, DDS
最近審閱：August 31, 2026
參考來源
- Neoral (cyclosporine) — Prescribing Information · DailyMed (U.S. National Library of Medicine)
- Effectiveness of substituting cyclosporin A with tacrolimus in reducing gingival overgrowth in renal transplant patients (Párraga-Linares, Almendros-Marqués, Berini-Aytés, Gay-Escoda, 2009) · Medicina Oral, Patología Oral y Cirugía Bucal (2009)
- Effectiveness of periodontal therapy in patients with drug-induced gingival overgrowth: Long-term results (Ilgenli, Atilla, Baylas, 1999) · Journal of Periodontology (1999)
本頁內容為一般患者教育。不能替代您的處方醫生、藥劑師或牙醫的建議。藥物資訊可能會變更；請與您的臨床團隊確認。