Steroids and inflammation

Methotrexate and your teeth

Generic name: Methotrexate · Class: Antifolate / DMARD

Methotrexate is used at low doses for autoimmune conditions like rheumatoid arthritis and psoriasis, and at higher doses for certain cancers.

Methotrexate is one of the most common causes of medication-induced mouth ulcers and mucositis. The mouth is one of the first places its effects show, because it acts on rapidly dividing cells, including the cells lining the mouth. Long-term use also affects healing and bleeding tendencies, which matters for dental procedures.

Methotrexate and dental care
Common questions patients have about Methotrexate.
Related medications
Talk to us about your medications
Bring your medication list to your next visit.

We review every patient’s medications at every visit and adjust treatment planning when it matters. If you are starting a new medication or have a procedure coming up, mention it and we’ll walk through what to expect.