Steroids and inflammation
Sirolimus (Rapamune) and your teeth
Generic name: Sirolimus · Class: mTOR inhibitor / immunosuppressant
Sirolimus is an mTOR inhibitor used after organ transplant to prevent rejection and increasingly in some cancers and rare diseases.
Sirolimus is one of the most common medication causes of recurrent aphthous-like mouth ulcers. Many transplant patients on sirolimus develop persistent mouth sores that significantly affect eating and quality of life. The ulcers respond to dose adjustment and topical care but rarely resolve fully while on the medication. Coordination with the transplant team is part of management.
Sirolimus (Rapamune) and dental care
Common questions patients have about Sirolimus (Rapamune).
Related medications
Talk to us about your medications
Bring your medication list to your next visit.
We review every patient’s medications at every visit and adjust treatment planning when it matters. If you are starting a new medication or have a procedure coming up, mention it and we’ll walk through what to expect.